Rudkin Brian B.
Brian B. Rudkin / DR2 - CNRS
Research interests
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
Member of Platforms
Selected Publications of Brian B. Rudkin
| Year |
Reference |
Title | Authors | Journal | PUB MED | ||
|---|---|---|---|---|---|---|---|
| 2007 | 6(3):451-9 | An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity | de Chassey B, Mikaelian I, Mathieu AL, Bickle M, Olivier D, Nègre D, Cosset FL, Rudkin BB, Colas P | Mol Cell Proteomics | - | ||
| 2012 | 7(7):485-91 | Dorsal root ganglion progenitors differentiate to gamma-aminobutyric acid- and choline acetyltransferase-positive neurons | Yu L, Ding Y, Spencer A, Ma J, Lu R, Rudkin BB, Yuan C | Neural Regen Res | - | ||
| 2004 | 70(4):1147-52 | Key role for cyclin-dependent kinases in the first and second meiotic divisions of rat spermatocytes | Godet M, Damestoy A, Mouradian S, Rudkin BB, Durand P | Biol Reprod | |||
| 2004 | 70(4):1147-52 | Key role for cyclin-dependent kinases in the first and second meiotic divisions of rat spermatocytes | Godet M, Damestoy A, Mouradian S, Rudkin BB, Durand P | Biol Reprod | - | ||
| 1999 | 73(10):8762-70 | Possible interactions between the NS-1 protein and tumor necrosis factor alpha pathways in erythroid cell apoptosis induced by human parvovirus B19 | Sol N, Le Junter J, Vassias I, Freyssinier JM, Thomas A, Prigent AF, Rudkin BB, Fichelson S, Morinet F | J Virol | - | ||
| 1996 | 785:298-300 | Expression of Trk receptors during cartilage differentiation | Mitsiadis TA, Wroblewski J, Urdiales JL, Becker E, Martin-Zanca D, Rudkin BB, Lendahl U | Ann N Y Acad Sci | - | ||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | |||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | - | ||
| 1989 | 8(11):3319-25 | Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation | Rudkin BB, Lazarovici P, Levi BZ, Abe Y, Fujita K, Guroff G | EMBO J | - | ||
| 1988 | 85(23):8860-4 | A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches | Jiricny J, Hughes M, Corman N, Rudkin BB | Proc Natl Acad Sci U S A | - | ||