Rudkin Brian B.
Brian B. Rudkin / DR2 - CNRS
Research interests
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
Member of Platforms
Selected Publications of Brian B. Rudkin
| Year | Reference |
Title |
Authors | Journal | PUB MED | ||
|---|---|---|---|---|---|---|---|
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | |||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | - | ||
| 1984 | 217(3):731-41 | Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells | Rudkin BB, Mamont PS, Seiler N | Biochem J | - | ||
| 1998 | pp100 - 106. IOS Press, Amsterdam | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Rudkin BB, Evan GI, Martin-Zanca D | Cancer Research Supported under Biomed1 | - | ||
| 1994 | A.-E. Baert et al. Ed | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Martin-Zanca D, Evan GI, Rudkin BB | European Union Biomedical and Health Research. The BIOMED 1 Programme | - | ||
| 2005 | 25(12):5106-18 | Critical role for Kalirin in nerve growth factor signaling through TrkA | Chakrabarti K, Lin R, Schiller NI, Wang Y, Koubi D, Fan YX, Rudkin BB, Johnson GR, Schiller MR | Mol Cell Biol | - | ||
| 1988 | pp. 273-277, Alan R. Liss, Inc | Correlation between the substrate specificity of a Hela mismatch binding protein and the efficiency of mismatch repair in vivo | Jiricny, J, Rudkin BB, Brown TC, Corman N | Mechanisms and Consequences of DNA Damage Processing | - | ||
| 1999 | 18(18):2872-82 | Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation | Billon N, Carlisi D, Datto MB, van Grunsven LA, Watt A, Wang XF, Rudkin BB | Oncogene | - | ||
| 1989 | 8(11):3319-25 | Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation | Rudkin BB, Lazarovici P, Levi BZ, Abe Y, Fujita K, Guroff G | EMBO J | - | ||
| 1998 | 18(17):6767-75 | Cell cycle phase-specific surface expression of nerve growth factor receptors TrkA and p75(NTR) | Urdiales JL, Becker E, Andrieu M, Thomas A, Jullien J, van Grunsven LA, Menut S, Evan GI, Martín-Zanca D, Rudkin BB | J Neurosci | - | ||