Rudkin Brian B.
Brian B. Rudkin / DR2 - CNRS
Research interests
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
Member of Platforms
Selected Publications of Brian B. Rudkin
Year |
Reference | Title | Authors | Journal | PUB MED | ||
|---|---|---|---|---|---|---|---|
| 1994 | A.-E. Baert et al. Ed | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Martin-Zanca D, Evan GI, Rudkin BB | European Union Biomedical and Health Research. The BIOMED 1 Programme | - | ||
| 1993 | 54(3):161-75 | Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar | Mitsiadis TA, Couble P, Dicou E, Rudkin BB, Magloire H | Differentiation | - | ||
| 1992 | 58(1):175-85 | Differential responses of the phosphorylation of ribosomal protein S6 to nerve growth factor and epidermal growth factor in PC12 cells | Mutoh T, Rudkin BB, Guroff G | J Neurochem | - | ||
| 1991 | 28(4):486-96 | Differentiation of PC12 cells with K-ras: comparison with nerve growth factor | Simpson DL, Dickens G, Doll S, Koizumi S, Tocco M, Okuda O, Oshima M, Rudkin BB, Brightman M, Guroff G | J Neurosci Res | - | ||
| 1991 | 285(2):170-5 | Regulation of protein synthesis at the elongation stage. New insights into the control of gene expression in eukaryotes | Ryazanov AG, Rudkin BB, Spirin AS | FEBS Lett | - | ||
| 1991 | 3:1-5 | To divide or not to divide: When, where and how. Molecular control of the cell cycle and cell differentiation | Rudkin BB | The New Biol | - | ||
| 1989 | 8(11):3319-25 | Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation | Rudkin BB, Lazarovici P, Levi BZ, Abe Y, Fujita K, Guroff G | EMBO J | - | ||
| 1989 | 24(1):49-58 | Differentiation of PC12 cells with v-src: comparison with nerve growth factor | Rausch DM, Dickens G, Doll S, Fujita K, Koizumi S, Rudkin BB, Tocco M, Eiden LE, Guroff G | J Neurosci Res | - | ||
| 1989 | 25(1):149-53 | Different patterns of G/T and A/C mismatch repair in simian cells correspond to the specificity of a mismatch binding protein isolated from simian and HeLa cells | Brown TC, Corman N, Rudkin BB, Jiricny J | Ann Ist Super Sanita | - | ||
| 1989 | Raven Press, Ltd., New York. 195-202 | Nerve growth factor-sensitive phosphorylations and the action of K-252a on PC12 cells | Koizumi S, Mutoh T, Ryazanov A, Rudkin BB, Guroff G | Trophic Factors and the Nervous System | - | ||