Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
|2015||2;8:2||Highly efficient method for gene delivery into mouse dorsal root ganglia neurons.||Yu L, Reynaud F, Falk J, Spencer A, Ding YD, Baumlé V, Lu R, Castellani V, Yuan C, Rudkin BB||Front Mol Neurosci||-|
|2011||33:983-987||Effect of Caveolin-1 on Proliferation and Survival of MCF-7 Breast||Lu R, Ma J, Zhang Y, Lu L, Spencer A, Cluet D, Rudkin BB, Yuan CG||Chin J Cell Biol||-|
|1991||3:1-5||To divide or not to divide: When, where and how. Molecular control of the cell cycle and cell differentiation||Rudkin BB||The New Biol||-|
|1986||5(4):725-31||Activation of ribosomal protein S6 phosphorylation during meiotic maturation of Xenopus laevis oocytes: in vitro ordered appearance of S6 phosphopeptides||Martin-Pérez J, Rudkin BB, Siegmann M, Thomas G||EMBO J||-|
|2009||535:373-88||Peptide aptamers for small molecule drug discovery||Bardou C, Borie C, Bickle M, Rudkin BB, Colas P||Methods Mol Biol||-|
|1980||54(2):127-39||Kinetics of the association of potential-sensitive dyes with model and energy-transducing membranes: implications for fast probe response times||Smith JC, Frank SJ, Bashford CL, Chance B, Rudkin BB||J Membr Biol||-|
|1993||54(3):161-75||Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar||Mitsiadis TA, Couble P, Dicou E, Rudkin BB, Magloire H||Differentiation||-|
|1992||58(1):175-85||Differential responses of the phosphorylation of ribosomal protein S6 to nerve growth factor and epidermal growth factor in PC12 cells||Mutoh T, Rudkin BB, Guroff G||J Neurochem||-|
|2007||6(11):1842-54||Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis||Com E, Lagadec C, Page A, El Yazidi-Belkoura I, Slomianny C, Spencer A, Hammache D, Rudkin BB, Hondermarck H||Mol Cell Proteomics||-|
|2007||6(12):2110-21||A comparative analysis of perturbations caused by a gene knock-out, a dominant negative allele, and a set of peptide aptamers||Abed N, Bickle M, Mari B, Schapira M, Sanjuan-España R, Robbe Sermesant K, Moncorgé O, Mouradian-Garcia S, Barbry P, Rudkin BB, Fauvarque MO, Michaud-Soret I, Colas P||Mol Cell Proteomics||-|