Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
|1993||54(3):161-75||Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar||Mitsiadis TA, Couble P, Dicou E, Rudkin BB, Magloire H||Differentiation||-|
|1989||8(11):3319-25||Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation||Rudkin BB, Lazarovici P, Levi BZ, Abe Y, Fujita K, Guroff G||EMBO J||-|
|1986||5(4):725-31||Activation of ribosomal protein S6 phosphorylation during meiotic maturation of Xenopus laevis oocytes: in vitro ordered appearance of S6 phosphopeptides||Martin-Pérez J, Rudkin BB, Siegmann M, Thomas G||EMBO J||-|
|2000||79(11):816-23||Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis||Godet M, Thomas A, Rudkin BB, Durand P||Eur J Cell Biol|
|2000||79(11):816-23||Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis||Godet M, Thomas A, Rudkin BB, Durand P||Eur J Cell Biol||-|
|1994||A.-E. Baert et al. Ed||Decision-Making in a cell: Proliferation, Differentiation, Apoptosis?||Martin-Zanca D, Evan GI, Rudkin BB||European Union Biomedical and Health Research. The BIOMED 1 Programme||-|
|1991||285(2):170-5||Regulation of protein synthesis at the elongation stage. New insights into the control of gene expression in eukaryotes||Ryazanov AG, Rudkin BB, Spirin AS||FEBS Lett||-|
|2015||2;8:2||Highly efficient method for gene delivery into mouse dorsal root ganglia neurons.||Yu L, Reynaud F, Falk J, Spencer A, Ding YD, Baumlé V, Lu R, Castellani V, Yuan C, Rudkin BB||Front Mol Neurosci||-|
|1999||10(7):1129-38||Retroviral vectors for the expression of two genes in human multipotent neural precursors and their differentiated neuronal and glial progeny||Derrington EA, López-Lastra M, Chapel-Fernandez S, Cosset FL, Belin MF, Rudkin BB, Darlix JL||Hum Gene Ther||-|
|2017||18(4): 693||Nerve Growth Factor Signaling from Membrane Microdomains to the Nucleus: Differential Regulation by Caveolins||Spencer A, Yu L, Guilli V, Reynaud F, Ding YD, Jullien J, Koubi D, Gauthier E, Cluet D, Rudkin BB, Falk J, Castellani V, Yuan CG||Int J Mol Sci||-|