Rudkin Brian B.
Brian B. Rudkin / DR2 - CNRS
Research interests
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
Member of Platforms
Selected Publications of Brian B. Rudkin
| Year | Reference | Title | Authors |
Journal |
PUB MED | ||
|---|---|---|---|---|---|---|---|
| 1991 | 285(2):170-5 | Regulation of protein synthesis at the elongation stage. New insights into the control of gene expression in eukaryotes | Ryazanov AG, Rudkin BB, Spirin AS | FEBS Lett | - | ||
| 1994 | A.-E. Baert et al. Ed | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Martin-Zanca D, Evan GI, Rudkin BB | European Union Biomedical and Health Research. The BIOMED 1 Programme | - | ||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | |||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | - | ||
| 1989 | 8(11):3319-25 | Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation | Rudkin BB, Lazarovici P, Levi BZ, Abe Y, Fujita K, Guroff G | EMBO J | - | ||
| 1986 | 5(4):725-31 | Activation of ribosomal protein S6 phosphorylation during meiotic maturation of Xenopus laevis oocytes: in vitro ordered appearance of S6 phosphopeptides | Martin-Pérez J, Rudkin BB, Siegmann M, Thomas G | EMBO J | - | ||
| 1993 | 54(3):161-75 | Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar | Mitsiadis TA, Couble P, Dicou E, Rudkin BB, Magloire H | Differentiation | - | ||
| 2011 | 33:983-987 | Effect of Caveolin-1 on Proliferation and Survival of MCF-7 Breast | Lu R, Ma J, Zhang Y, Lu L, Spencer A, Cluet D, Rudkin BB, Yuan CG | Chin J Cell Biol | - | ||
| 1998 | pp100 - 106. IOS Press, Amsterdam | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Rudkin BB, Evan GI, Martin-Zanca D | Cancer Research Supported under Biomed1 | - | ||
| 2014 | 15 Suppl 14:S5 | EXACT2: the semantics of biomedical protocols | Soldatova LN, Nadis D, King RD, Basu PS, Haddi E, Baumlé V, Saunders NJ, Marwan W, Rudkin BB | BMC Bioinformatics | - | ||