Rudkin Brian B.
Brian B. Rudkin / DR2 - CNRS
Research interests
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
Member of Platforms
Selected Publications of Brian B. Rudkin
| Year | Reference | Title | Authors |
Journal |
PUB MED | ||
|---|---|---|---|---|---|---|---|
| 1989 | 25(1):149-53 | Different patterns of G/T and A/C mismatch repair in simian cells correspond to the specificity of a mismatch binding protein isolated from simian and HeLa cells | Brown TC, Corman N, Rudkin BB, Jiricny J | Ann Ist Super Sanita | - | ||
| 1996 | 785:298-300 | Expression of Trk receptors during cartilage differentiation | Mitsiadis TA, Wroblewski J, Urdiales JL, Becker E, Martin-Zanca D, Rudkin BB, Lendahl U | Ann N Y Acad Sci | - | ||
| 1999 | 262(1):157-62 | Phosphorylation by p44 MAP Kinase/ERK1 stimulates CBP histone acetyl transferase activity in vitro | Ait-Si-Ali S, Carlisi D, Ramirez S, Upegui-Gonzalez LC, Duquet A, Robin P, Rudkin BB, Harel-Bellan A, Trouche D | Biochem Biophys Res Commun | - | ||
| 1984 | 217(3):731-41 | Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells | Rudkin BB, Mamont PS, Seiler N | Biochem J | - | ||
| 2004 | 70(4):1147-52 | Key role for cyclin-dependent kinases in the first and second meiotic divisions of rat spermatocytes | Godet M, Damestoy A, Mouradian S, Rudkin BB, Durand P | Biol Reprod | |||
| 2004 | 70(4):1147-52 | Key role for cyclin-dependent kinases in the first and second meiotic divisions of rat spermatocytes | Godet M, Damestoy A, Mouradian S, Rudkin BB, Durand P | Biol Reprod | - | ||
| 1999 | pp254 - 255. Directorate General Research ed. | Proliferation, Differentiation, Apoptosis : What's the difference? | Rudkin BB | Biomedical and health research programme 1994-1998, Summaries of projects supported under Biomed2, Volume 1 | - | ||
| 2014 | 15 Suppl 14:S5 | EXACT2: the semantics of biomedical protocols | Soldatova LN, Nadis D, King RD, Basu PS, Haddi E, Baumlé V, Saunders NJ, Marwan W, Rudkin BB | BMC Bioinformatics | - | ||
| 1998 | pp100 - 106. IOS Press, Amsterdam | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Rudkin BB, Evan GI, Martin-Zanca D | Cancer Research Supported under Biomed1 | - | ||
| 2011 | 33:983-987 | Effect of Caveolin-1 on Proliferation and Survival of MCF-7 Breast | Lu R, Ma J, Zhang Y, Lu L, Spencer A, Cluet D, Rudkin BB, Yuan CG | Chin J Cell Biol | - | ||