Rudkin Brian B.
Brian B. Rudkin / DR2 - CNRS
Research interests
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
Member of Platforms
Selected Publications of Brian B. Rudkin
| Year | Reference |
Title |
Authors | Journal | PUB MED | ||
|---|---|---|---|---|---|---|---|
| 1988 | pp. 273-277, Alan R. Liss, Inc | Correlation between the substrate specificity of a Hela mismatch binding protein and the efficiency of mismatch repair in vivo | Jiricny, J, Rudkin BB, Brown TC, Corman N | Mechanisms and Consequences of DNA Damage Processing | - | ||
| 2005 | 25(12):5106-18 | Critical role for Kalirin in nerve growth factor signaling through TrkA | Chakrabarti K, Lin R, Schiller NI, Wang Y, Koubi D, Fan YX, Rudkin BB, Johnson GR, Schiller MR | Mol Cell Biol | - | ||
| 1998 | pp100 - 106. IOS Press, Amsterdam | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Rudkin BB, Evan GI, Martin-Zanca D | Cancer Research Supported under Biomed1 | - | ||
| 1994 | A.-E. Baert et al. Ed | Decision-Making in a cell: Proliferation, Differentiation, Apoptosis? | Martin-Zanca D, Evan GI, Rudkin BB | European Union Biomedical and Health Research. The BIOMED 1 Programme | - | ||
| 1984 | 217(3):731-41 | Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells | Rudkin BB, Mamont PS, Seiler N | Biochem J | - | ||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | |||
| 2000 | 79(11):816-23 | Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis | Godet M, Thomas A, Rudkin BB, Durand P | Eur J Cell Biol | - | ||
| 1989 | 25(1):149-53 | Different patterns of G/T and A/C mismatch repair in simian cells correspond to the specificity of a mismatch binding protein isolated from simian and HeLa cells | Brown TC, Corman N, Rudkin BB, Jiricny J | Ann Ist Super Sanita | - | ||
| 1992 | 58(1):175-85 | Differential responses of the phosphorylation of ribosomal protein S6 to nerve growth factor and epidermal growth factor in PC12 cells | Mutoh T, Rudkin BB, Guroff G | J Neurochem | - | ||
| 1991 | 28(4):486-96 | Differentiation of PC12 cells with K-ras: comparison with nerve growth factor | Simpson DL, Dickens G, Doll S, Koizumi S, Tocco M, Okuda O, Oshima M, Rudkin BB, Brightman M, Guroff G | J Neurosci Res | - | ||