Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
|1993||54(3):161-75||Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar||Mitsiadis TA, Couble P, Dicou E, Rudkin BB, Magloire H||Differentiation||-|
|1980||54(2):127-39||Kinetics of the association of potential-sensitive dyes with model and energy-transducing membranes: implications for fast probe response times||Smith JC, Frank SJ, Bashford CL, Chance B, Rudkin BB||J Membr Biol||-|
|2009||535:373-88||Peptide aptamers for small molecule drug discovery||Bardou C, Borie C, Bickle M, Rudkin BB, Colas P||Methods Mol Biol||-|
|1986||5(4):725-31||Activation of ribosomal protein S6 phosphorylation during meiotic maturation of Xenopus laevis oocytes: in vitro ordered appearance of S6 phosphopeptides||Martin-Pérez J, Rudkin BB, Siegmann M, Thomas G||EMBO J||-|
|1991||3:1-5||To divide or not to divide: When, where and how. Molecular control of the cell cycle and cell differentiation||Rudkin BB||The New Biol||-|
|2011||33:983-987||Effect of Caveolin-1 on Proliferation and Survival of MCF-7 Breast||Lu R, Ma J, Zhang Y, Lu L, Spencer A, Cluet D, Rudkin BB, Yuan CG||Chin J Cell Biol||-|
|2015||2;8:2||Highly efficient method for gene delivery into mouse dorsal root ganglia neurons.||Yu L, Reynaud F, Falk J, Spencer A, Ding YD, Baumlé V, Lu R, Castellani V, Yuan C, Rudkin BB||Front Mol Neurosci||-|
|1991||285(2):170-5||Regulation of protein synthesis at the elongation stage. New insights into the control of gene expression in eukaryotes||Ryazanov AG, Rudkin BB, Spirin AS||FEBS Lett||-|
|1991||28(4):486-96||Differentiation of PC12 cells with K-ras: comparison with nerve growth factor||Simpson DL, Dickens G, Doll S, Koizumi S, Tocco M, Okuda O, Oshima M, Rudkin BB, Brightman M, Guroff G||J Neurosci Res||-|
|2003||278(10):8706-16||Trafficking of TrkA-green fluorescent protein chimerae during nerve growth factor-induced differentiation||Jullien J, Guili V, Derrington EA, Darlix JL, Reichardt LF, Rudkin BB||J Biol Chem||-|