Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014.
The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide aptamers, to potential patient benefit in the context of the StemGamE platform.
The present transfer focus: • neurodegenerative diseases - e.g. ALS (Amyotrophic Lateral Sclerosis - Maladie de Charcot) • stimulation of the immune response e.g. for adoptive cell therapy of certain cancers • enhancement of safety of the use of embryonic stem cell-derived cultures for potential therapeutic benefit.
|2014||15 Suppl 14:S5||EXACT2: the semantics of biomedical protocols||Soldatova LN, Nadis D, King RD, Basu PS, Haddi E, Baumlé V, Saunders NJ, Marwan W, Rudkin BB||BMC Bioinformatics||-|
|1996||12(6):1347-56||Effect of nerve growth factor on the expression of cell cycle regulatory proteins in PC12 cells: dissection of the neurotrophic response from the anti-mitogenic response||van Grunsven LA, Billon N, Savatier P, Thomas A, Urdiales JL, Rudkin BB||Oncogene|
|1996||12(6):1347-56||Effect of nerve growth factor on the expression of cell cycle regulatory proteins in PC12 cells: dissection of the neurotrophic response from the anti-mitogenic response||van Grunsven LA, Billon N, Savatier P, Thomas A, Urdiales JL, Rudkin BB||Oncogene||-|
|2011||33:983-987||Effect of Caveolin-1 on Proliferation and Survival of MCF-7 Breast||Lu R, Ma J, Zhang Y, Lu L, Spencer A, Cluet D, Rudkin BB, Yuan CG||Chin J Cell Biol||-|
|2012||7(7):485-91||Dorsal root ganglion progenitors differentiate to gamma-aminobutyric acid- and choline acetyltransferase-positive neurons||Yu L, Ding Y, Spencer A, Ma J, Lu R, Rudkin BB, Yuan C||Neural Regen Res||-|
|1997||14(3):265-75||Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutations||Rossel M, Pasini A, Chappuis S, Geneste O, Fournier L, Schuffenecker I, Takahashi M, van Grunsven LA, Urdiales JL, Rudkin BB, Lenoir GM, Billaud M||Oncogene||-|
|1989||24(1):49-58||Differentiation of PC12 cells with v-src: comparison with nerve growth factor||Rausch DM, Dickens G, Doll S, Fujita K, Koizumi S, Rudkin BB, Tocco M, Eiden LE, Guroff G||J Neurosci Res||-|
|1991||28(4):486-96||Differentiation of PC12 cells with K-ras: comparison with nerve growth factor||Simpson DL, Dickens G, Doll S, Koizumi S, Tocco M, Okuda O, Oshima M, Rudkin BB, Brightman M, Guroff G||J Neurosci Res||-|
|1992||58(1):175-85||Differential responses of the phosphorylation of ribosomal protein S6 to nerve growth factor and epidermal growth factor in PC12 cells||Mutoh T, Rudkin BB, Guroff G||J Neurochem||-|
|1989||25(1):149-53||Different patterns of G/T and A/C mismatch repair in simian cells correspond to the specificity of a mismatch binding protein isolated from simian and HeLa cells||Brown TC, Corman N, Rudkin BB, Jiricny J||Ann Ist Super Sanita||-|