Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
|2000||22(4):346-56||Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments||Haddjeri N, Szabo ST, de Montigny C, Blier P||Neuropsychopharmacology||-|
|2020||pp 1-19||Antidepressants: Molecular Aspects of SSRIs||Etievant A, Haddjeri N, Lau T||NeuroPsychopharmacotherapy||-|
|2015||131:136-42||A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant||Bétry C, Overstreet D, Haddjeri N, Pehrson AL, Bundgaard C, Sanchez C, Mørk A||Pharmacol Biochem Behav||-|
|2019||17(3):e2006211||Rods contribute to the light-induced phase shift of the retinal clock in mammals||Calligaro H, Coutanson C, Najjar RP, Mazzaro N, Cooper HM, Haddjeri N, Felder-Schmittbuhl MP, Dkhissi-Benyahya O||PLoS Biol||-|
|2015||10(3):e0118009||Effect of the multimodal acting antidepressant vortioxetine on rat hippocampal plasticity and recognition memory||Bétry C, Etiévant A, Pehrson A, Sánchez C, Haddjeri N||Prog Neuropsychopharmacol Biol Psychiatry||-|
|2013||43:40-8||Protein kinase C regulates mood-related behaviors and adult hippocampal cell proliferation in rats||Abrial E, Etievant A, Bétry C, Scarna H, Lucas G, Haddjeri N, Lambás-Señas L||Prog Neuropsychopharmacol Biol Psychiatry||-|
|2021||https://doi.org/10.1016/bs.pbr.2021.01.002||Role of central serotonin and noradrenaline interactions in the antidepressants’ action: Electrophysiological and neurochemical evidence||Delcourte S, Etievant A, Haddjeri N||Progress in Brain Research||-|