Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
|2001||50(3):191-9||Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission||Haddjeri N, Blier P||Biol Psychiatry||-|
|2019||6(3):ENEURO.0021-19.2019. doi: 10.1523/ENEURO.0021-19.2019||Serotonin Neuronal Function from the Bed to the Bench: Is This Really a Mirrored Way?||Adeline Etievant, Thorsten Lau, Guillaume Lucas, Nasser Haddjeri||eNeuro||-|
|2016||80(6):e43-e44||Deep Brain Stimulation for Depression: Is It a Gray or White "Matter"?||Etiévant A, Lucas G, Haddjeri N||Biol Psychiatry||-|
|2015||89:382-90||Involvement of 5-HT₇ receptors in vortioxetine's modulation of circadian rhythms and episodic memory in rodents||Westrich L, Haddjeri N, Dkhissi-Benyahya O, Sánchez C||Neuropharmacology||-|
|2016||9:509||The Role of Astroglia in the Antidepressant Action of Deep Brain Stimulation||Etiévant A, Lucas G, Dkhissi-Benyahya O, Haddjeri N||Front Cell Neurosci||-|
|2021||https://doi.org/10.1016/bs.pbr.2021.01.002||Role of central serotonin and noradrenaline interactions in the antidepressants’ action: Electrophysiological and neurochemical evidence||Delcourte S, Etievant A, Haddjeri N||Progress in Brain Research||-|
|2020||pp 1-19||Antidepressants: Molecular Aspects of SSRIs||Etievant A, Haddjeri N, Lau T||NeuroPsychopharmacotherapy||-|