Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
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Title | Authors | Journal | PUB MED | ||
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2020 | 229(1):e13440. doi: 10.1111/apha.13440 | Genetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugs | Benjamin Portal, Sarah Delcourte, Renaud Rovera, Camille Lejards, Sebastien Bullich, Cécile E Malnou, Nasser Haddjeri, Nicole Déglon, Bruno P Guiard | Acta Physiol (Oxf) | - | ||
2018 | 23(3):587-596 | Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects | Kanzari A, Bourcier-Lucas C, Freyssin A, Abrous DN, Haddjeri N, Lucas G | Mol Psychiatry | - | ||
2018 | 24(12):1129-1139 | The novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor-dependent partial agonist actions on rat mesencephalic dopamine neuronal activity | Delcourte S, Ashby CR Jr, Rovera R, Kiss B, Adham N, Farkas B, Haddjeri N | CNS Neurosci Ther | - | ||
2006 | 26(20):5370-82 | GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression | Serrano A, Haddjeri N, Lacaille JC, Robitaille R | J Neurosci | - | ||
2004 | 29(10):1800-6 | Electrophysiological evidence for the tonic activation of 5-HT(1A) autoreceptors in the rat dorsal raphe nucleus | Haddjeri N, Lavoie N, Blier P | Neuropsychopharmacology | - | ||
2005 | 30(7):1269-77 | Effects of acute and long-term administration of escitalopram and citalopram on serotonin neurotransmission: an in vivo electrophysiological study in rat brain | El Mansari M, Sánchez C, Chouvet G, Renaud B, Haddjeri N | Neuropsychopharmacology | - | ||
2011 | 36(6):1275-88 | Pharmacological blockade of 5-HT7 receptors as a putative fast acting antidepressant strategy | Mnie-Filali O, Faure C, Lambás-Señas L, El Mansari M, Belblidia H, Gondard E, Etiévant A, Scarna H, Didier A, Berod A, Blier P, Haddjeri N | Neuropsychopharmacology | - | ||
2017 | 4(2) | Stress Models of Depression: A Question of Bad Timing | Delcourte S, Dkhissi-Benyahya O, Cooper H, Haddjeri N | eNeuro | - | ||
2013 | 43:40-8 | Protein kinase C regulates mood-related behaviors and adult hippocampal cell proliferation in rats | Abrial E, Etievant A, Bétry C, Scarna H, Lucas G, Haddjeri N, Lambás-Señas L | Prog Neuropsychopharmacol Biol Psychiatry | - | ||
1999 | 45(9):1163-9 | Modulation of the firing activity of rat serotonin and noradrenaline neurons by (+/-)pindolol | Haddjeri N, de Montigny C, Blier P | Biol Psychiatry | - | ||