Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
|2016||80(6):e43-e44||Deep Brain Stimulation for Depression: Is It a Gray or White "Matter"?||Etiévant A, Lucas G, Haddjeri N||Biol Psychiatry||-|
|2015||2(8):898-908||Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation||Etiévant A, Oosterhof C, Bétry C, Abrial E, Novo-Perez M, Rovera R, Scarna H, Devader C, Mazella J, Wegener G, Sánchez C, Dkhissi-Benyahya O, Gronfier C, Coizet V, Beaulieu JM, Blier P, Lucas G, Haddjeri N||EBioMedicine||-|
|2013||14(11):1295-307||Astrocytes and gliotransmitters: new players in the treatment of major depression?||Etiévant A, Lambás-Señas L, Scarna H, Lucas G, Haddjeri N||Curr Drug Targets||-|
|2020||pp 1-19||Antidepressants: Molecular Aspects of SSRIs||Etievant A, Haddjeri N, Lau T||NeuroPsychopharmacotherapy||-|
|2015||131:136-42||A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant||Bétry C, Overstreet D, Haddjeri N, Pehrson AL, Bundgaard C, Sanchez C, Mørk A||Pharmacol Biochem Behav||-|
|2019||6(3):ENEURO.0021-19.2019. doi: 10.1523/ENEURO.0021-19.2019||Serotonin Neuronal Function from the Bed to the Bench: Is This Really a Mirrored Way?||Adeline Etievant, Thorsten Lau, Guillaume Lucas, Nasser Haddjeri||eNeuro||-|
|2021||22(2):E937||Learned Immobility Produces Enduring Impairment of the HPA Axis Reactivity in Mice without Replicating the Broad Spectrum of Depressive-Like Phenotype||Sébastien Bullich, Sarah Delcourte, Nasser Haddjeri, Bruno P Guiard||Int J Mol Sci||-|