Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
Year | Reference |
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Authors | Journal | PUB MED | ||
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2016 | 9:509 | The Role of Astroglia in the Antidepressant Action of Deep Brain Stimulation | Etiévant A, Lucas G, Dkhissi-Benyahya O, Haddjeri N | Front Cell Neurosci | - | ||
2013 | 16(5):1115-27 | The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism | Bétry C, Pehrson AL, Etiévant A, Ebert B, Sánchez C, Haddjeri N | Int J Neuropsychopharmacol | - | ||
2018 | 24(12):1129-1139 | The novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor-dependent partial agonist actions on rat mesencephalic dopamine neuronal activity | Delcourte S, Ashby CR Jr, Rovera R, Kiss B, Adham N, Farkas B, Haddjeri N | CNS Neurosci Ther | - | ||
2001 | 50(3):191-9 | Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission | Haddjeri N, Blier P | Biol Psychiatry | - | ||
2017 | 4(2) | Stress Models of Depression: A Question of Bad Timing | Delcourte S, Dkhissi-Benyahya O, Cooper H, Haddjeri N | eNeuro | - | ||
2021 | https://doi.org/10.1016/bs.pbr.2021.01.002 | Role of central serotonin and noradrenaline interactions in the antidepressants’ action: Electrophysiological and neurochemical evidence | Delcourte S, Etievant A, Haddjeri N | Progress in Brain Research | - | ||
2019 | 17(3):e2006211 | Rods contribute to the light-induced phase shift of the retinal clock in mammals | Calligaro H, Coutanson C, Najjar RP, Mazzaro N, Cooper HM, Haddjeri N, Felder-Schmittbuhl MP, Dkhissi-Benyahya O | PLoS Biol | - | ||
2013 | 43:40-8 | Protein kinase C regulates mood-related behaviors and adult hippocampal cell proliferation in rats | Abrial E, Etievant A, Bétry C, Scarna H, Lucas G, Haddjeri N, Lambás-Señas L | Prog Neuropsychopharmacol Biol Psychiatry | - | ||
2014 | 18(2) | Protein kinase C inhibition rescues manic-like behaviors and hippocampal cell proliferation deficits in the sleep deprivation model of mania | Abrial E, Bétourné A, Etiévant A, Lucas G, Scarna H, Lambás-Señas L, Haddjeri N | Int J Neuropsychopharmacol | - | ||
2011 | 36(6):1275-88 | Pharmacological blockade of 5-HT7 receptors as a putative fast acting antidepressant strategy | Mnie-Filali O, Faure C, Lambás-Señas L, El Mansari M, Belblidia H, Gondard E, Etiévant A, Scarna H, Didier A, Berod A, Blier P, Haddjeri N | Neuropsychopharmacology | - | ||