Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
|2019||17(3):e2006211||Rods contribute to the light-induced phase shift of the retinal clock in mammals||Calligaro H, Coutanson C, Najjar RP, Mazzaro N, Cooper HM, Haddjeri N, Felder-Schmittbuhl MP, Dkhissi-Benyahya O||PLoS Biol||-|
|2021||https://doi.org/10.1016/bs.pbr.2021.01.002||Role of central serotonin and noradrenaline interactions in the antidepressants’ action: Electrophysiological and neurochemical evidence||Delcourte S, Etievant A, Haddjeri N||Progress in Brain Research||-|
|2017||4(2)||Stress Models of Depression: A Question of Bad Timing||Delcourte S, Dkhissi-Benyahya O, Cooper H, Haddjeri N||eNeuro||-|
|2001||50(3):191-9||Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission||Haddjeri N, Blier P||Biol Psychiatry||-|
|2018||24(12):1129-1139||The novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor-dependent partial agonist actions on rat mesencephalic dopamine neuronal activity||Delcourte S, Ashby CR Jr, Rovera R, Kiss B, Adham N, Farkas B, Haddjeri N||CNS Neurosci Ther||-|
|2013||16(5):1115-27||The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism||Bétry C, Pehrson AL, Etiévant A, Ebert B, Sánchez C, Haddjeri N||Int J Neuropsychopharmacol||-|
|2016||9:509||The Role of Astroglia in the Antidepressant Action of Deep Brain Stimulation||Etiévant A, Lucas G, Dkhissi-Benyahya O, Haddjeri N||Front Cell Neurosci||-|