Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.
Year | Reference |
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Authors | Journal | PUB MED | ||
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2021 | 22(2):E937 | Learned Immobility Produces Enduring Impairment of the HPA Axis Reactivity in Mice without Replicating the Broad Spectrum of Depressive-Like Phenotype | Sébastien Bullich, Sarah Delcourte, Nasser Haddjeri, Bruno P Guiard | Int J Mol Sci | - | ||
2019 | 6(3):ENEURO.0021-19.2019. doi: 10.1523/ENEURO.0021-19.2019 | Serotonin Neuronal Function from the Bed to the Bench: Is This Really a Mirrored Way? | Adeline Etievant, Thorsten Lau, Guillaume Lucas, Nasser Haddjeri | eNeuro | - | ||
2015 | 131:136-42 | A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant | Bétry C, Overstreet D, Haddjeri N, Pehrson AL, Bundgaard C, Sanchez C, Mørk A | Pharmacol Biochem Behav | - | ||
2020 | pp 1-19 | Antidepressants: Molecular Aspects of SSRIs | Etievant A, Haddjeri N, Lau T | NeuroPsychopharmacotherapy | - | ||
2013 | 14(11):1295-307 | Astrocytes and gliotransmitters: new players in the treatment of major depression? | Etiévant A, Lambás-Señas L, Scarna H, Lucas G, Haddjeri N | Curr Drug Targets | - | ||
2015 | 2(8):898-908 | Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation | Etiévant A, Oosterhof C, Bétry C, Abrial E, Novo-Perez M, Rovera R, Scarna H, Devader C, Mazella J, Wegener G, Sánchez C, Dkhissi-Benyahya O, Gronfier C, Coizet V, Beaulieu JM, Blier P, Lucas G, Haddjeri N | EBioMedicine | - | ||
2016 | 80(6):e43-e44 | Deep Brain Stimulation for Depression: Is It a Gray or White "Matter"? | Etiévant A, Lucas G, Haddjeri N | Biol Psychiatry | - | ||
2015 | 10(3):e0118009 | Effect of the multimodal acting antidepressant vortioxetine on rat hippocampal plasticity and recognition memory | Bétry C, Etiévant A, Pehrson A, Sánchez C, Haddjeri N | Prog Neuropsychopharmacol Biol Psychiatry | - | ||
2005 | 30(7):1269-77 | Effects of acute and long-term administration of escitalopram and citalopram on serotonin neurotransmission: an in vivo electrophysiological study in rat brain | El Mansari M, Sánchez C, Chouvet G, Renaud B, Haddjeri N | Neuropsychopharmacology | - | ||
2004 | 29(10):1800-6 | Electrophysiological evidence for the tonic activation of 5-HT(1A) autoreceptors in the rat dorsal raphe nucleus | Haddjeri N, Lavoie N, Blier P | Neuropsychopharmacology | - | ||