Bourillot Pierre-Yves
Pierre-Yves Bourillot / CRCN - CNRS
Research interests
He obtained his PhD from the University of Lyon in 1997. After a 3-year postdoc at the University of Cambridge (UK), he joined the Savatier team in 2000. He studies LIF/STAT3 signalling in mouse and human ES cells. In collaboration with Hongwei Chen, he reprogrammed human ES cells to ground-like state of pluripotency. He also studies the role of long non-coding RNAs in ground state pluripotency.
Member of SBRI Teams
Selected Publications of Pierre-Yves Bourillot
| Year | Reference | Title | Authors |
Journal |
PUB MED | ||
|---|---|---|---|---|---|---|---|
| 2015 | 6:7095 | Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency | Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, Rognard C, Hochard A, Voisin S, Fontaine E, Mure M, Afanassieff M, Cleroux E, Guibert S, Chen J, Vallot C, Acloque H, Genthon C, Donnadieu C, De Vos J, Sanlaville D, Guérin JF, Weber M, Stanton LW, Rougeulle C, Pain B, Bourillot PY, Savatier P | Nat Commun | - | ||
| 2014 | 5:3719 | Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells | Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Chen J, Jauch R, Bogu GK, Nolden T, Himmelbauer H, Xavier Doss M, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hübner N, Stanton LW, Real FX, Bourillot PY, Savatier P | Nat Commun | - | ||
| 2001 | 413(6858):797-803 | Morphogen gradient interpretation | Gurdon JB, Bourillot PY | Nature | |||
| 1995 | 23(24):4939-45 | RBP-J kappa repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2 | Waltzer L, Bourillot PY, Sergeant A, Manet E | Nucleic Acids Res | |||
| 2009 | 4(9):e6804 | The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation | Schulz H, Kolde R, Adler P, Aksoy I, Anastassiadis K, Bader M, Billon N, Boeuf H, Bourillot PY, Buchholz F, Dani C, Doss MX, Forrester L, Gitton M, Henrique D, Hescheler J, Himmelbauer H, Hübner N, Karantzali E, Kretsovali A, Lubitz S, Pradier L, Rai M, Reimand J, Rolletschek A, Sachinidis A, Savatier P, Stewart F, Storm MP, Trouillas M, Vilo J, Welham MJ, Winkler J, Wobus AM, Hatzopoulos AK | PLoS One | |||
| 2021 | 16(1):56-74 | Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells | Irène Aksoy, Cloé Rognard, Anaïs Moulin, Guillaume Marcy, Etienne Masfaraud, Florence Wianny, Véronique Cortay, Angèle Bellemin-Ménard, Nathalie Doerflinger, Manon Dirheimer, Chloé Mayère , Pierre-Yves Bourillot, Cian Lynch, Olivier Raineteau, Thierry Joly, Colette Dehay, Manuel Serrano, Marielle Afanassieff, Pierre Savatier | Stem Cell Reports | - | ||
| 2016 | 16(3):557-67 | Epigenetic status of H19/IGF2 and SNRPN imprinted genes in aborted and successfully derived embryonic stem cell lines in non-human primates | Wianny F, Blachère T, Godet M, Guillermas R, Cortay V, Bourillot PY, Lefèvre A, Savatier P, Dehay C | Stem Cell Res | - | ||
| 2013 | 10(1):118-31 | A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency | Coronado D, Godet M, Bourillot PY, Tapponnier Y, Bernat A, Petit M, Afanassieff M, Markossian S, Malashicheva A, Iacone R, Anastassiadis K, Savatier P | Stem Cell Res | - | ||
| 2009 | 27(8):1760-71 | Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog | Bourillot PY, Aksoy I, Schreiber V, Wianny F, Schulz H, Hummel O, Hubner N, Savatier P | Stem Cells | |||
| 2007 | 25(12):2996-3004 | Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3 | Aksoy I, Sakabedoyan C, Bourillot PY, Malashicheva AB, Mancip J, Knoblauch K, Afanassieff M, Savatier P | Stem Cells | |||