He obtained his PhD from the University of Lyon in 1997. After a 3-year postdoc at the University of Cambridge (UK), he joined the Savatier team in 2000. He studies LIF/STAT3 signalling in mouse and human ES cells. In collaboration with Hongwei Chen, he reprogrammed human ES cells to ground-like state of pluripotency. He also studies the role of long non-coding RNAs in ground state pluripotency.
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Reference | Title | Authors | Journal | PUB MED | ||
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1995 | 23(24):4939-45 | RBP-J kappa repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2 | Waltzer L, Bourillot PY, Sergeant A, Manet E | Nucleic Acids Res | |||
1998 | 79 ( Pt 2):363-70 | Transcriptional repression by the Epstein-Barr virus EBNA3A protein tethered to DNA does not require RBP-Jkappa | Bourillot PY, Waltzer L, Sergeant A, Manet E | J Gen Virol | |||
1998 | 28(2):129-37 | EBV genes and B cell proliferation | Manet E, Bourillot PY, Waltzer L, Sergeant A | Crit Rev Oncol Hematol | |||
2000 | 94(1-2):133-46 | The Xenopus eomesodermin promoter and its concentration-dependent response to activin | Ryan K, Garrett N, Bourillot P, Stennard F, Gurdon JB | Mech Dev | |||
2001 | 413(6858):797-803 | Morphogen gradient interpretation | Gurdon JB, Bourillot PY | Nature | |||
2001 | 21(12):3901-12 | Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling | Shimizu K, Bourillot PY, Nielsen SJ, Zorn AM, Gurdon JB | Mol Cell Biol | - | ||
2002 | 129(9):2167-80 | A changing morphogen gradient is interpreted by continuous transduction flow | Bourillot PY, Garrett N, Gurdon JB | Development | |||
2007 | 25(12):2996-3004 | Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3 | Aksoy I, Sakabedoyan C, Bourillot PY, Malashicheva AB, Mancip J, Knoblauch K, Afanassieff M, Savatier P | Stem Cells | |||
2007 | 282(9):6265-73 | Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells | Storm MP, Bone HK, Beck CG, Bourillot PY, Schreiber V, Damiano T, Nelson A, Savatier P, Welham MJ | J Biol Chem | |||
2009 | 27(8):1760-71 | Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog | Bourillot PY, Aksoy I, Schreiber V, Wianny F, Schulz H, Hummel O, Hubner N, Savatier P | Stem Cells | |||