She obtained her PhD from the University of Lyon in 2008. After a 5-year postdoc at the Genome Institute of Singapore, where she studied different aspects of somatic cell reprogramming, she joined the Savatier team in 2013 to work on pluripotency in non-human primates. She studies the transcriptome of the macaque pre-implantation, and reprograms ES cell lines suitable for the generation of somatic chimaeras in the rhesus macaque.
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Reference | Title | Authors | Journal | PUB MED | ||
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2021 | 16(1):56-74 | Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells | Irène Aksoy, Cloé Rognard, Anaïs Moulin, Guillaume Marcy, Etienne Masfaraud, Florence Wianny, Véronique Cortay, Angèle Bellemin-Ménard, Nathalie Doerflinger, Manon Dirheimer, Chloé Mayère , Pierre-Yves Bourillot, Cian Lynch, Olivier Raineteau, Thierry Joly, Colette Dehay, Manuel Serrano, Marielle Afanassieff, Pierre Savatier | Stem Cell Reports | - | ||
2018 | 34(11):944-953 | Fifty shades of pluripotency | Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier P | Med Sci (Paris) | - | ||
2017 | 24:106-117 | Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors | Tapponnier Y, Afanassieff M, Aksoy I, Aubry M, Moulin A, Medjani L, Bouchereau W, Osteil P, Nurse-Francis J, Oikonomakos I, Joly T, Jouneau L, Archilla C, Schmaltz-Panneau B, Peynot N, Barasc H, Pinton A, Lecardonnel J, Gocza E, Beaujean N, Duranthon V, Savatier P | Stem Cell Res | - | ||
2017 | 26(2):367-382 | Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders | Aksoy I, Utami KH, Winata CL, Hilmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V | Hum Mol Genet | - | ||