Bourillot Pierre-Yves
Pierre-Yves Bourillot / CRCN - CNRS
Research interests
He obtained his PhD from the University of Lyon in 1997. After a 3-year postdoc at the University of Cambridge (UK), he joined the Savatier team in 2000. He studies LIF/STAT3 signalling in mouse and human ES cells. In collaboration with Hongwei Chen, he reprogrammed human ES cells to ground-like state of pluripotency. He also studies the role of long non-coding RNAs in ground state pluripotency.
Member of SBRI Teams
Selected Publications of Pierre-Yves Bourillot
Year |
Reference | Title | Authors | Journal | PUB MED | ||
|---|---|---|---|---|---|---|---|
| 2021 | 16(1):56-74 | Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells | Irène Aksoy, Cloé Rognard, Anaïs Moulin, Guillaume Marcy, Etienne Masfaraud, Florence Wianny, Véronique Cortay, Angèle Bellemin-Ménard, Nathalie Doerflinger, Manon Dirheimer, Chloé Mayère , Pierre-Yves Bourillot, Cian Lynch, Olivier Raineteau, Thierry Joly, Colette Dehay, Manuel Serrano, Marielle Afanassieff, Pierre Savatier | Stem Cell Reports | - | ||
| 2019 | 18(20):2697-2712 | Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells | Gonnot F, Langer D, Bourillot PY, Doerflinger N, Savatier P | Cell Cycle | - | ||
| 2018 | 34(11):944-953 | Fifty shades of pluripotency | Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier P | Med Sci (Paris) | - | ||
| 2016 | 16(3):557-67 | Epigenetic status of H19/IGF2 and SNRPN imprinted genes in aborted and successfully derived embryonic stem cell lines in non-human primates | Wianny F, Blachère T, Godet M, Guillermas R, Cortay V, Bourillot PY, Lefèvre A, Savatier P, Dehay C | Stem Cell Res | - | ||
| 2015 | 6:7095 | Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency | Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, Rognard C, Hochard A, Voisin S, Fontaine E, Mure M, Afanassieff M, Cleroux E, Guibert S, Chen J, Vallot C, Acloque H, Genthon C, Donnadieu C, De Vos J, Sanlaville D, Guérin JF, Weber M, Stanton LW, Rougeulle C, Pain B, Bourillot PY, Savatier P | Nat Commun | - | ||
| 2014 | 5:3719 | Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells | Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Chen J, Jauch R, Bogu GK, Nolden T, Himmelbauer H, Xavier Doss M, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hübner N, Stanton LW, Real FX, Bourillot PY, Savatier P | Nat Commun | - | ||
| 2013 | 10(1):118-31 | A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency | Coronado D, Godet M, Bourillot PY, Tapponnier Y, Bernat A, Petit M, Afanassieff M, Markossian S, Malashicheva A, Iacone R, Anastassiadis K, Savatier P | Stem Cell Res | - | ||
| 2011 | 81(3):142-52 | Embryonic stem cells in non-human primates: An overview of neural differentiation potential | Wianny F, Bourillot PY, Dehay C | Differentiation | |||
| 2010 | 8:125 | Krüppel-like transcription factors and control of pluripotency | Bourillot PY, Savatier P | BMC Biol | |||
| 2009 | 27(8):1760-71 | Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog | Bourillot PY, Aksoy I, Schreiber V, Wianny F, Schulz H, Hummel O, Hubner N, Savatier P | Stem Cells | |||