After a Ph.D. (2001) in Developmental Biology on the Pierre-et-Marie Currie Campus in Paris, I worked as a Post-Doc at the Roslin Institute with Prof. Ian WILMUT (Scotland). I joined the French National Institute of Agronomic Research in 2003, to develop studies on chromatin remodeling during embryonic development, upon fertilization or cloning (by somatic cell nuclear transfer, SCNT). Since 2016, I supervise projects on epigenetic reprogramming at the Stem Cell & Brain Research Institute (SBRI), in Lyon. My expertise mostly relies on embryo micromanipulations (IVF, ICSI, SCNT, chimerism), pluripotent stem cells (ESC, iPSC) & the use/development of image analysis tools, in murine and rabbit species.
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Reference | Title | Authors | Journal | PUB MED | ||
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2020 | 22(7):767-778 | Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3 | Adam Burton, Vincent Brochard, Carmen Galan, Elias R Ruiz-Morales, Quirze Rovira, Diego Rodriguez-Terrones, Kai Kruse, Stéphanie Le Gras, Vishnu S Udayakumar, Hang Gyeong Chin, André Eid, Xiaoyu Liu, Chenfei Wang, Shaorong Gao, Sriharsa Pradhan, Juan M Vaquerizas, Nathalie Beaujean, Thomas Jenuwein, Maria-Elena Torres-Padilla | Nat Cell Biol | - | ||
2020 | 389(2):111908 | Embryo-derived and induced pluripotent stem cells: Towards naive pluripotency and chimeric competency in rabbits | Marielle Afanassieff, Florence Perold, Wilhelm Bouchereau, Antoine Cadiou, Nathalie Beaujean | Exp Cell Res | - | ||
2019 | REP-19-0245.R1 | Heat shock during in vitro maturation induces chromatin modifications in the bovine embryo | Camargo LSA, Aguirre-Lavin T, Adenot P, Araujo TD, Mendes VRA, Louro ID, Beaujean N, Souza ED | Reproduction | - | ||
2018 | 1708:59-80 | Antibody-Based Detection of Global Nuclear DNA Methylation in Cells, Tissue Sections, and Mammalian Embryos | Beaujean N, Salvaing J, Hadi NAA, Pennings S | Methods Mol Biol | - | ||
2018 | 8(1):5776 | Contrasting epigenetic states of heterochromatin in the different types of mouse pluripotent stem cells | Tosolini M, Brochard V, Adenot P, Chebrout M, Grillo G, Navia V, Beaujean N, Francastel C, Bonnet-Garnier A, Jouneau A | Sci Rep | - | ||
2018 | 127(3):387-403 | Three-dimensional analysis of nuclear heterochromatin distribution during early development in the rabbit | Bonnet-Garnier A, Kiêu K, Aguirre-Lavin T, Tar K, Flores P, Liu Z, Peynot N, Chebrout M, Dinnyés A, Duranthon V, Beaujean N | Chromosoma | - | ||
2018 | 34(11):944-953 | Fifty shades of pluripotency | Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier P | Med Sci (Paris) | - | ||
2017 | 24:106-117 | Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors | Tapponnier Y, Afanassieff M, Aksoy I, Aubry M, Moulin A, Medjani L, Bouchereau W, Osteil P, Nurse-Francis J, Oikonomakos I, Joly T, Jouneau L, Archilla C, Schmaltz-Panneau B, Peynot N, Barasc H, Pinton A, Lecardonnel J, Gocza E, Beaujean N, Duranthon V, Savatier P | Stem Cell Res | - | ||
2017 | 154(6):807-814 | Embryo cell allocation patterns are not altered by biopsy but can be linked with further development | Sepulveda-Rincon LP, Islam N, Marsters P, Campbell BK, Beaujean N, Maalouf WE | Reproduction | - | ||
2017 | 65(5):873-884 | Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways | Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon J | Mol Cell | - | ||