She earned her PhD in Paris, in 2001, and then worked as a post-doc at the Roslin Institute (Scotland). She joined INRA in 2003, at Jouy-en-Josas, to develop studies on chromatin remodeling during preimplantation development , mainly in murine and rabbit/bovine species. She is very experienced in the analysis of epigenetic reprogramming by powerful image analysis tools. Since her arrival at SBRI her project is to study chromatin & epigenetic reprogramming to totipotency. Model systems include embryos upon fertilization or nuclear transfer (cloning) as well as after pluripotency induction in somatic cells (iPSC) of various mammalian species.
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Reference | Title | Authors | Journal | PUB MED | ||
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2019 | REP-19-0245.R1 | Heat shock during in vitro maturation induces chromatin modifications in the bovine embryo | Camargo LSA, Aguirre-Lavin T, Adenot P, Araujo TD, Mendes VRA, Louro ID, Beaujean N, Souza ED | Reproduction | - | ||
2018 | 1708:59-80 | Antibody-Based Detection of Global Nuclear DNA Methylation in Cells, Tissue Sections, and Mammalian Embryos | Beaujean N, Salvaing J, Hadi NAA, Pennings S | Methods Mol Biol | - | ||
2018 | 8(1):5776 | Contrasting epigenetic states of heterochromatin in the different types of mouse pluripotent stem cells | Tosolini M, Brochard V, Adenot P, Chebrout M, Grillo G, Navia V, Beaujean N, Francastel C, Bonnet-Garnier A, Jouneau A | Sci Rep | - | ||
2018 | 127(3):387-403 | Three-dimensional analysis of nuclear heterochromatin distribution during early development in the rabbit | Bonnet-Garnier A, Kiêu K, Aguirre-Lavin T, Tar K, Flores P, Liu Z, Peynot N, Chebrout M, Dinnyés A, Duranthon V, Beaujean N | Chromosoma | - | ||
2018 | 34(11):944-953 | Fifty shades of pluripotency | Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier P | Med Sci (Paris) | - | ||
2017 | 24:106-117 | Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors | Tapponnier Y, Afanassieff M, Aksoy I, Aubry M, Moulin A, Medjani L, Bouchereau W, Osteil P, Nurse-Francis J, Oikonomakos I, Joly T, Jouneau L, Archilla C, Schmaltz-Panneau B, Peynot N, Barasc H, Pinton A, Lecardonnel J, Gocza E, Beaujean N, Duranthon V, Savatier P | Stem Cell Res | - | ||
2017 | 154(6):807-814 | Embryo cell allocation patterns are not altered by biopsy but can be linked with further development | Sepulveda-Rincon LP, Islam N, Marsters P, Campbell BK, Beaujean N, Maalouf WE | Reproduction | - | ||
2017 | 65(5):873-884 | Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways | Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon J | Mol Cell | - | ||
2016 | 95(6):123 | Random Allocation of Blastomere Descendants to the Trophectoderm and ICM of the Bovine Blastocyst | Sepulveda-Rincon LP, Dube D, Adenot P, Laffont L, Ruffini S, Gall L, Campbell BK, Duranthon V, Beaujean N, Maalouf WE | Biol Reprod | - | ||
2016 | 31(11):2471-2483 | Assessment of 'one-step' versus 'sequential' embryo culture conditions through embryonic genome methylation and hydroxymethylation changes | Salvaing J, Peynot N, Bedhane MN, Veniel S, Pellier E, Boulesteix C, Beaujean N, Daniel N, Duranthon V | Hum Reprod | - | ||