StemGamE is a biotechnology research platform, joint funded by INSERM and INRA, dedicated to deriving embryonic stem (ES) and induced pluripotent stem (iPS) cell lines in non murine species, including primates and livestocks. ES cells are derived in the rabbit to develop an ES cell-based transgenic technology in farm animals. ES and iPS cells are derived in human and rhesus monkey. They are used to assess both the efficacy and the safety of cell therapy in a monkey model of Parkinson disease. Beside, PrimaStem offers training to research teams in the field of non murine ES cell culture and engineering.
| Marielle Afanassieff || |
CR1 INRA. She obtained her PhD from the University of Lyon in 1991. After a postdoc at the "City of Hope" Hospital in California, she joined the Savatier team in 2004. She now studies the transcriptome of the rabbit pre-implantation, and engineers ES cell lines suitable for the generation of somatic and germline chimaeras in rabbits.
| Mehdi Benchaib || |
| Thierry Blachere || |
Molecular biology, DNA methylation, imprinted genes.
| Cyrielle Fournier || |
| Murielle Godet || |
Genomic imprinting in stem cells.
| Jean-François Guerin || |
| Hervé Lejeune || |
| Jacqueline Lornage || |
Cryopreservation of ovaries and oocytes development
| Marie-Hélène Perrard || |
| Brian B. RUDKIN || |
Research Director at the CNRS within the Stem Cell and Brain Research Institute (SBRI), Inserm U1208, University of Lyon and Co-Founder, in 2009, of the Joint Laboratory on Neuropathogenesis along with Prof. Chonggang YUAN at East China Normal University (ECNU) in Shanghai, integrated into the Key Laboratory of Brain Functional Genomics at the ECNU in January 2014. The main objective is the transfer of fundamental discoveries using small antibody mimetics called peptide ...
| Pierre Savatier || |
DR2 INSERM, Team leader. He obtained his PhD from the University of Lyon in 1986. He joined INSERM in 2004 as an AVENIR team leader, and the same year he was awarded the “Coup d’Elan pour la recherche” from the Bettencourt Foundation. His team participates in two laboratory of excellence (LabEx): DEVweCAN and CORTEX. His is responsible for PrimaStem, a technological platform specialized in pluripotent stem cells in primates. PrimaStem participates ...
Selected Publications of Team members : |