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Parution de "Les mécanismes du sommeil"

Published on June 19, 2013


Claude Gronfier a participé à l'écriture d'un ouvrage sur le sommeil qui est paru cette semaine...
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 European funded projects 

Seco - Co-ordinator Henry Kennedy

 

SECO is a four-year project funded by the Seventh Research Program (FP7) of the European Union. It involves 7 research groups in 5 countries. SECO is one of several projects funded under the FP7 initiative on BIO-ICT Convergence.
SECO (short for Self Construction) will propose methods for designing and implementing self-constructing systems. It will begin by examining existing self-constructing systems such as the mammalian neocortex, and move towards a theoretical framework for abstract specification of arbitrary self-constructing systems.
As circuits get exponentially smaller and faster, we face exponential increases in their production cost. Current hardware methodologies demand extremely low failure rates for individual components, yet when fabricating huge circuits, yields are still low.
Nature has solved these problems. Our neocortex, a cellular computer that generates intelligent behavior, constructs and configures itself starting from a single precursor cell, based on genetic information and interactions with its environment. Understanding this process would revolutionize computer technology. Progress in developmental neuroscience now permits a reverse-engineering approach, abstracting nature's principles into systems of our own design. Here we propose some first steps towards understanding these developmental construction mechanisms so that we can transpose them into novel software design technologies.
We will demonstrate, by a fusion of experimental neuroscience, detailed physical simulation, and theoretical analysis, the principles by which a population of real or artificial neurons can grow and assemble themselves into functioning circuits.



Henry Kennedy

SBRI investigates the development, function and repair of neuronal circuits involved in cognition, motor control and biological rhythms and researches the structural foundations of computation in the cortex. We seek to develop embryonic stem cell based therapies so as to reverse the effects of brain lesions leading to the motor and cognitive deficits found in neurological disease including Parkinson's.


Veronique Cortay

I am a research assistant engineer. My interest concerns the study of cortical development. I analyse proliferation, differentiation and migration in the developing cortex using cell biology techniques. I routinely perform immunohistochemistry, dissociated cell culture, organotypic culture of embryonic brain and time-lapse videomicroscopy. Recently I have focused my efforts on 2 photons imaging of GFP/RFP expressing precursors on organotypic slices.

Besides performing ...

Colette Dehay

Team leader


Nathalie Doerflinger

Molecular biology : cloning, PCR and qPCR (on DNA, RT or single cell cytoplasm), LCM, RNA microarray, RNAi (siRNA and shRNA), ISH, IHC,...


Razvan Gamanut PhD Student

Elodie Gautier PHD Student

Pascale Giroud

Analysis of cortical connectivity


Cyril Huissoud

Selected Publications of Team members :