CORTEX International Meeting 2013Published on April 22, 2013
LabEx CORTEX is organising an International Conference in Lyon next June....
Reproduction, epigenesis and development
One of the conducting thread that permits evolution from the oocyte up to embryonic stem (ES) cells is epigenetic remodeling, particularly via the parental imprinting process.
| Annick Elisabeth Lefèvre || |
Genomic imprinting in oocytes and stem cells
| Mohamed Al-Khtib || |
Despite the success of Assisted Reproductive Technologies, recent data suggest a link between the use of ART* and diseases related to epigenetic errors.To evaluate the impact of ART* on DNA methylation, we analyzed:
1) the methylation profile of 2 imprinted ...
| Thierry Blachere || |
Molecular biology, DNA methylation, imprinted genes.
| Hervé Lejeune || |
| Jacqueline Lornage || |
Cryopreservation of ovaries and oocytes development
| Bruno Salle || |
Ovary autograf and development
Selected Publications of Team members : |
Borghol N, Blachere T, Lefevre A. (2008) Transcriptional and epigenetic status of protamine 1 and 2 genes following round spermatids injection into mouse oocytes Genomics 91 (5): 415-422 download
Courbiere B, Caquant L, Mazoyer C, Franck M, Lornage J, Salle B. (2008) Difficulties improving ovarian functional recovery by microvascular transplantation and whole ovary vitrification Fertil Steril download
Khoureiry R, Ibala-Rhomdane S, Mery L, Blachere T, Guerin JF, Lornage J, Lefevre A. (2008) Dynamic CpG methylation of the KCNQ1OT1 gene during maturation of human oocytes J Med Genet 45 (9): 583-8 download
Baudot A, Courbiere B, Odagescu V, Salle B, Mazoyer C, Massardier J, Lornage J. (2007) Towards whole sheep ovary cryopreservation Cryobiology 55 (3) : 236-48 download
Borghol, N. Lornage, J. Blachere, T. Sophie Garret, A. Lefevre, A. (2006) Epigenetic status of the H19 locus in human oocytes following in vitro maturation Genomics 87 (3): 417 - 426 download
Courbiere B, Odagescu V, Baudot A, Massardier J, Mazoyer C, Salle B, Lornage J. (2006) Cryopreservation of the ovary by vitrification as an alternative to slow-cooling protocols Fertil Steril 86 (4 suppl) download
Bordes A, Lornage J, Demirci B, Franck M, Courbiere B, Guerin JF, Salle B. (2005) Normal gestations and live births after orthotopic autograft of vitrified-warmed hemi-ovaries into ewes Hum Reprod 20 (10): 2745-8 download
Courbiere B, Massardier J, Salle B, Mazoyer C, Guerin JF, Lornage J. (2005) Follicular viability and histological assessment after cryopreservation of whole sheep ovaries with vascular pedicle by vitrification Fertil Steril 84 (suppl 2) 1065-71 download
Salle B, Demirci B, Franck M, Berthollet C, Lornage J. (2003) Long-term follow-up of cryopreserved hemi-ovary autografts in ewes: pregnancies, births, and histologic assessment Fertil Steril 80 (1): 172-7 download
Salle, B. Demirci, B. Franck, M. Rudigoz, R. C. Guerin, J. F. Lornage, J. (2002) Normal pregnancies and live births after autograft of frozen-thawed hemi-ovaries into ewes Fertil Steril 77 (2): 403-8 download
Ziyyat A, Lefevre A (2001) Differential gene expression in pre-implantation embryos from mouse oocytes injected with round spermatids or spermatozoa Hum Reprod 16 (7): 1449-56 download
Salle B, Lornage J, Demirci B, Vaudoyer F, Poirel MT, Franck M, Rudigoz RC, Guerin JF (1999) Restoration of ovarian steroid secretion and histologic assessment after freezing, thawing, and autograft of a hemi-ovary in sheep Fertil Steril 72 (2): 366-70 download
Salle B, Lornage J, Franck M, Isoard L, Rudigoz RC, Guerin JF (1998) Freezing, thawing, and autograft of ovarian fragments in sheep: preliminary experiments and histologic assessment Fertil Steril 70 (1):124-8 download