SBRI Stem-cell and Brain Research Institute - France (Lyon)

Platform
:
Chronobiology

Human chronobiology Research facility (Hospital Edouard Herriot, Lyon):

Research facility for short to long-term clinical studies of the human circadian timing system and sleep in complete time isolation. Studies conducted in the facility are focused on understanding the effects of light on sleep, circadian and non-visual physiology, in healthy young and aged individuals, in patients with ocular diseases, and in shift workers. The facility is affiliated to the network of European Centres on Human Chronobiology. Local teams investigating sleep physiology have indicated an interest in conducting human studies in the facility.

Facility/equipment includes 3 rooms (~250 m2), 4 beds, 3 computer-controlled ganzfled-type lighting setup for photic exposure, 3 digital polysomnography devices for sleep and wake EEG/ECG recordings, 1 experimental head-mounted device for pupillary reflex recording, devices for temperature recording, 3 laptop computers for cognitive and memory testing, equipment for visual evaluation (color vision, acuity, contrast), equipment for biological sample processing (refrigerated centrifuge, freezer).

Human non-visual physiology Research facility (Inserm U846, Bron):

Research facility for short studies of human visual and non-visual physiology. Studies conducted in the facility are focused on understanding the effects of light the pupillary light reflex on sleep, circadian and non-visual physiology, in healthy young and aged individuals, in patients with ocular diseases, and in shift workers. The facility is affiliated to the network of European Centres on Human Chronobiology. The facility also include a setup to measure lens density in vivo in humans. Local ophthalmologists have indicated an interest in having lens density measured in their patients. A patent is currently being field on the lens density method and setup.

Facility/equipment includes 2 rooms (~20 m2), 1 computer-controlled setup for pupillary reflex recordings, 1 computer controlled setup for lens density measurement, 2 spectrophotometers, 2 luxmeters, 1 photometer.

 

Platform
: Chronobiology

Members list

Howard Cooper
Team Leader / DRE

Claude Gronfier
CR1

Abhishek Prayag
PhD Student