Pierre Savatier

Bourillot PY, Aksoy I, Schreiber V, Wianny F, Schulz H, Hummel O, Hubner N, Savatier P. (2009) Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with nanog Stem Cell 27: 1760-1771 download

Schulz H et al (2009) The FunGenES database: a genomic resource for mouse Embryonic Stem Cells differentiation PloS One, 4(9): e6804. download

Marchand M, Schröder I, Markossian S, Skoudy A. Nègre D. Cosset FL, Real FX, Wobus AM, Savatier P (2009) Mouse ES cells overexpressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages Int. J. Dev. Biol. 53:569-578. download

Wianny F, Bernat A, Huissoud C, Marcy G, Markossian S, Cortay V, Giroud P, Leviel V, Kennedy H, Savatier P, Dehay C (2008) Derivation and cloning of a Novel Rhesus ES cell line stably expressing Tau-GFP Stem Cells 26(6):1444-53 download

Rovira M, Delaspre F, Massumi M, Serra SA, Valverde MA, Lloreta J, Dufresne M, Payré B, Konieczny SF, Savatier P, Real FX, Skoudy A. (2008) Murine Embryonic Stem Cell-Derived Pancreatic Acinar Cells Recapitulate Features of Early Pancreatic Differentiation. Gastroenterology. 25

Aksoy I, Sakabedoyan C, Bourillot PY, Malashicheva AB, Mancip J, Knoblauch K, Afanassieff M, Savatier P (2007) Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases pim-1 and pim-3. Stem Cells 25(12):2996-3004 download

Storm MP, Bone HK, Beck CG, Bourillot PY, Schreiber V, Damiano R, Nelson A, Savatier P, Welham MJ (2007) Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells. J Biol Chem 282(9):6265-73. download

Rovira M, Jané-Valbuena J, Marchand M, Savatier P, Real FX, Skoudy A. (2007) Viral-mediated coexpression of Pdx1 and p48 regulates exocrine pancreatic differentiation in mouse ES cells. Cloning Stem Cells.9(3):327-38 download

Savatier P. (2007) What's new on ES cells? Med Sci (Paris). 23(4):358-9 download

Fluckiger AC, Marcy G, Marchand M, Negre D, Cosset FL, Mitalipov S, Wolf D, Savatier P, Dehay C (2006) Cell cycle features of Primate Embryonic Stem Cells Stem Cells 24(3):547-556 download

Lukaszewicz A, Savatier P, Cortay V, Giroud P, Huissoud C, Berland M, Kennedy H, Dehay C (2005) G1 phase regulation, Area-Specific cell cycle control, and Cytoarchitectonics in the Primate Cortex Neuron 47 (3):353-64 download

Moriscot C, de Fraipont F, Richard MJ, Marchand M, Savatier P, Bosco D, Favrot M, Benhamou PY. (2005) Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro. Stem Cells 23(4):594-603. download

Skoudy A, Rovira M, Savatier P, Martin F, León-Quinto T, Soria B, Real FX. (2004) Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cells. Biochem J 379(Pt 3):749-56. download

Savatier, P.; Malashicheva, A. (2004) Cell-cycle control in embryonic stem cells Handbook of stem cells Vol: 2: Embryonic Stem Cells download

Fluckiger AC, Dehay C, Savatier P. (2003) Embryonic stem cells and cell replacement therapies in the nervous system Med Sci (Paris). 19(6-7):699-708 download

Lukaszewicz A, Savatier P, Cortay V, Kennedy H, Dehay C (2002) Contrasting Effects of Basic Fibroblast Growth Factor and Neurotrophin 3 on Cell Cycle Kinetics of Mouse Cortical Stem Cells J Neurosci 22:6610-22 download

Jirmanova L, Afanassieff M, Gobert-Gosse S, Markossian S, Savatier P (2002) Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. Oncogene 21:5515-28 download

Burdon T, Smith AG, Savatier P (2002) Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 12:432-8 download

Savatier P, Lapillonne H, Jirmanova L, Vitelli L, Samarut J (2002) Analysis of the cell cycle in mouse embryonic stem cells. Methods Mol Biol.185:27-33 download

Savatier P, Afanassieff M (2002) Cell cycle control and self-renewal of embryonic stem cells J Soc Biol 196(1): 117-23.

Dehay C, Savatier P, Cortay V, Kennedy H (2001) Cell-cycle kinetics of neocortical precursors are influenced by embryonic thalamic axons J Neurosci 21(1):201-14 download

Vallier L, Mancip J, Markossian S, Lukaszewicz A, Dehay C, Metzger D, Chambon P, Samarut J, Savatier P (2001) An efficient system for conditional gene expression in embryonic stem cells and their in vitro and in vivo differentiated derivatives. Proc Nat Acad Sci USA 98:2467-2472 download

Goumans MJ, Ward-Van O, Wianny F, Savatier P, Zwijsen A, Mummery CL (1998) Mouse embryonic stem cells with aberrant transforming growth factor beta signalling exhibit impaired differentiation in vitro and in vivo. Differentiation 63(3):101-13 download

Wianny F, Real FX, Mummery CL, Van Rooijen M, Lahti J, Samarut J, Savatier P (1998) G1 phase regulation, Cyclin D1, Cyclin D2 and Cyclin D3: up-regulation at gastrulation and dynamic expression during neurolation. Dev Dyn 212:49-62 download

Goumans MJ, Ward-Van O, Wianny F, Savatier P, Zwijsen A, Mummery CL (1998) Embryonic stem cells with aberrant TGFBeta signalling exhibit impaired differentiation in vitro and in vivo. Differentiation 63(3):101-13 download

Kennedy H, Dehay C, Savatier P. (1998) Modulation du cycle cellulaire et spécification des aires du neocortex Arch Physiol Biochem 106:1-5

Chassande O, Fraichard A, Gauthier K, Flamant F, Legrand C, Savatier P, Laudet V, Samarut J. (1997) Identification of transcripts initiated from an internal promoter in the c-erbA alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities. Mol Endocrinol. 11(9):1278-90 download

Savatier P, Lapillonne H, van Grunsven LA, Rudkin BB, Samarut J (1996) Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 12:309-322 download

Rouault JP, Falette N, Guéhenneux F, Guillot C, Rimokh R, Wang Q, Berthet C, Moyret-Lalle C, Savatier P, Pain B, Shaw P, Berger R, Samarut J, Magaud JP, Ozturk M, Samarut C, Puisieux A. (1996) Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway. Nat Genet. 14(4):482-6 download

van Grunsven LA, Billon N, Savatier P, Thomas A, Urdiales JL, Rudkin BB. (1996) Effect of nerve growth factor on the expression of cell cycle regulatory proteins in PC12 cells: dissection of the neurotrophic response from the anti-mitogenic response. Oncogene. 12(6):1347-56 download

Fraichard A, Chassande O, Bilbault G, Dehay C, Savatier P, Samarut J (1995) In vitro differentiation of ES cells into glial cells and functional neurons. J Cell Sci 108:3181-8 download

Cosset FL, Legras C, Chebloune Y, Savatier P, Thoraval P, Thomas JL, Samarut J, Nigon VM, Verdier G. (1990) A new avian leukosis virus-based packaging cell line that uses two separate transcomplementing helper genomes. J Virol. 64(3):1070-8 download

Savatier P, Morgenstern J, Beddington RS. (1990) Permissiveness to murine leukemia, virus expression during preimplantation and early postimplantation mouse development. Development. 109(3):655-65 download

Benchaib M, Mallet F, Thoraval P, Savatier P, Xiao JH, Verdier G, Samarut J, Nigon V. (1989) Avian retroviral vectors derived from avian defective leukemia virus: role of the translational context of the inserted gene on efficiency of the vectors. Virology. 169(1):15-26 download

Savatier P, Bagnis C, Thoraval P, Poncet D, Belakebi M, Mallet F, Legras C, Cosset FL, Thomas JL, Chebloune Y, et al. (1989) Generation of a helper cell line for packaging avian leukosis virus-based vectors. J Virol. 63(2):513-22 download

Savatier P, Trabuchet G, Chebloune Y, Faure C, Verdier G, Nigon VM. (1987) Nucleotide sequence of the beta-globin genes in gorilla and macaque: the origin of nucleotide polymorphisms in human. J Mol Evol.24(4):309-18 download

Savatier P, Trabuchet G, Chebloune Y, Faure C, Verdier G, Nigon VM. (1987) Nucleotide sequence of the delta-beta-globin intergenic segment in the macaque: structure and evolutionary rates in higher primates. J Mol Evol.24(4):297-308 download

Thoraval P, Savatier P, Xiao JH, Mallet F, Samarut J, Verdier G, Nigon V. (1987) Partial nucleotide sequence of the avian erythroblastosis virus (AEV ES4). Nucleic Acids Res. 15(22):9612 download

Trabuchet G, Chebloune Y, Savatier P, Lachuer J, Faure C, Verdier G, Nigon VM. (1987) Recent insertion of an Alu sequence in the beta-globin gene cluster of the gorilla. J Mol Evol. 25(4):288-91 download

Savatier P, Trabuchet G, Faure C, Chebloune Y, Gouy M, Verdier G, Nigon VM (1985) Evolution of the primate beta-globin gene region. High rate of variation in CpG dinucleotides and in short repeated sequences between man and chimpanzee. J Mol Biol. 182(1):21-9 download