Marie Rothe

I’m interested in understanding how decision making is completed, i.e. how value is computed depending on different reward parameters (probability, cost, quantity, quality, etc.), where different information are stored and analysed to be used and how the different brain regions involved in this process interact.
My researches focus on two prefrontal areas (dlPFC and ACC) and consist in studying their activities and interactions during decision making. To understand the mechanisms underlying this process, we work with different level of the neuronal activity, I specially use the local field potentials (LFP) analysis coming from intracerebral recordings during a problem solving task. I test possible correlations 1) between power modulations in different frequency bands and the different cognitive steps of the decision process and 2) between power modulation and the different value parameters of the reward engaged. I consider LFP in two different ways: LFP as a marker of local activity searching for links with single unit activities, and LFP as a reflection of intra-areal and inter-area communication l. To study such interactions I search for cross-frequencies correlations in the dlPFC, ACC and between both regions.