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Conference by Adrien Meguerditchian

Published on March 28, 2017

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Jacqueline Lornage

Position: Associate Professor

Company: Inserm u846

Mailing Address:
Laboratoire de Biologie de la Reproduction, Faculté de Médecine
8 Avenue Rockefeller
69373 - Lyon Cedex 08 - France
External Link:

StemGamE - Platforms

Research interest

Cryopreservation of ovaries and oocytes development

Brosse A, Le Chatton M, Morel Y, Hadj A, Bordes A, du Mesnildot P, Weryha G, Berthillier J, Malik S, Kassai-Koupai B, Lornage J, Salle B, Plotton I (2014) Correlation between Plasma and Follicular Dehydroepiandrosterone (DHEA) Concentrations And Oocyte/embryo Quality in Women Undergoing In vitro Fertilization. J Clin Endocr Metab, in press
Khoueiry R, Ibala-Romdhane S, Al-Khtib M, Blachere T, Lornage J, Guerin JF, Lefevre A (2013) Abnormal methylation of KCNQ1OT1 and differential methylation of H19 imprinting control regions in human ICSI embryos Zygote 21:129-138.
Torre A, Ben Brahim F, Popowski T, Boudjenah R, Salle B, Lornage J (2013) Factors related to unstained areas in whole ewe ovaries perfused with a metabolic marker. Hum Reprod, 28:423-429
Al-Khtib M, Perret A, Khoueiry R, Ibala-Romdhane S, Blachère T, Greze C, Lornage J, Lefèvre A (2011) Vitrification at the germinal vesicle stage does not affect the methylation profile of H19 and KCNQ1OT1 imprinting centers in human oocytes subsequently matured in vitro Fertility and sterility 95(6): 1955-60 download
Merdassi G, Mazoyer C, Guerin JF, Saad A, Salle B, Lornage J (2011) Examination of viability and quality of ovarian tissue after cryopreservation using simple laboratory methods in ewe. Reprod Biol Endocrinol 9:78
Massardier J, Courbiere B, Lornage J, Mazoyer C, Poirel MT, Martinot S, Franck M, Salle B. (2010) Technical Aspects of Laparoscopic Ovarian Autograft in Ewes After Cryopreservation by Slow-Cooling Protocol Reprod Domest Anim, 45: 8 -12
Santos RR, Amorim C, Cecconi S, Fassbender M, Imhof M, Lornage J, Paris M, Schoenfeldt V, Martinez-Madrid B (2010) Cryopreservation of ovarian tissue: an emerging technology for female germline preservation of endangered species and breeds. Anim Reprod Sci 122:151-163
Courbiere B, Caquant L, Mazoyer C, Franck M, Lornage J, Salle B. (2009) Difficulties improving ovarian functional recovery by microvascular transplantation and whole ovary vitrification Fertil Steril, 91:2697:2706 download
Dieterich K, Zouari R, Harbuz R, Vialard F, Martinez D, Bellayou H, Prisant N, Zoghmar A, Guichaoua MR, Koscinski I, Kharouf M, Noruzinia M, Nadifi S, Sefiani A, Lornage J, Zahi M, Viville S, Sele B, Jouk PS, Jacob MC, Escalier D, Nikas Y, Hennebicq S, Lu (2009) The Aurora Kinase C c.144delC mutation causes meiosis I arrest in men and is frequent in the North African population Hum Mol Genet 18:1301-1309
Bourlet T, Lornage J, Maertens A, Garret AS, Saoudin H, Tardy JC, Jimenez C, Guerin JF, Pozzetto B, Levy R (2009) Prospective evaluation of the threat related to the use of seminal fractions from hepatitis C virus-infected men in assisted reproductive techniques Hum Reprod 24:530-535
Khoureiry R, Ibala-Rhomdane S, Mery L, Blachere T, Guerin JF, Lornage J, Lefevre A. (2008) Dynamic CpG methylation of the KCNQ1OT1 gene during maturation of human oocytes J Med Genet 45 (9): 583-8 download
Neto V, Buff S, Lornage J, Bottollier B, Guerin P, Joly T. (2008) Effects of different freezing parameters on the morphology and viability of preantral follicles after cryopreservation of doe rabbit ovarian tissue Fertil Steril 89(5 - suppl1): 1348-56 download
Mazoyer C, Courbiere B, Salle B, Smitz J, Lornage J. (2008) State of the art on in vitro folliculogenesis in mouse Gynecol Obstet Fertil 36(1): 6-16 download
Benchaib M, Lornage J, Mazoyer C, Lejeune H, Salle B , Guerin JF (2007) Sperm deoxyribonucleic acid fragmentation as a prognostic indicator of assisted reproductive technology outcome Fertil Steril 87(1): 93-100 download
Baudot A, Courbiere B, Odagescu V, Salle B, Mazoyer C, Massardier J, Lornage J. (2007) Towards whole sheep ovary cryopreservation Cryobiology 55 (3) : 236-48 download
Mery L, Lefevre A, Benchaib M, Demirci B, Salle B, Guerin JF, Lornage J. (2007) Follicular growth in vitro: detection of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) during in vitro culture of ovine cortical slices Mol Reprod Dev 74(6): 767-74 download
Lornage J, Salle B. (2007) Ovarian and oocyte cryopreservation Curr Opin Obstet Gynecol 19(4): 390-4
Borghol, N. Lornage, J. Blachere, T. Sophie Garret, A. Lefevre, A. (2006) Epigenetic status of the H19 locus in human oocytes following in vitro maturation Genomics 87 (3): 417 - 426 download
Courbiere B, Odagescu V, Baudot A, Massardier J, Mazoyer C, Salle B, Lornage J. (2006) Cryopreservation of the ovary by vitrification as an alternative to slow-cooling protocols Fertil Steril 86 (4 suppl) download
Lornage J, Courbiere B, Mazoyer C, Odagescu V, Baudot A, Bordes A, Poirel MT, Franck M, Salle B. (2006) Ovarian tissue vitrification: Cortex and whole ovary in sheep Gynecol Obstet Fertil 34(9): 746-53
Lornage J (2006) In vitro maturation: the French experience (Maturation in vitro: l'expérience française) J Gynecol Obstet Biol Reprod (Paris) download
Bordes A, Lornage J, Demirci B, Franck M, Courbiere B, Guerin JF, Salle B. (2005) Normal gestations and live births after orthotopic autograft of vitrified-warmed hemi-ovaries into ewes Hum Reprod 20 (10): 2745-8 download
Courbiere B, Massardier J, Salle B, Mazoyer C, Guerin JF, Lornage J. (2005) Follicular viability and histological assessment after cryopreservation of whole sheep ovaries with vascular pedicle by vitrification Fertil Steril 84 (suppl 2) 1065-71 download
Benchaib M, Braun V, Ressnikof D, Lornage J, Durand P, Niveleau A, Guerin JF (2005) Influence of global sperm DNA methylation on IVF results Hum Reprod 20(3): 768-73 download
Neto V, Guerin P, Lornage J, Corrao N, Buff S, Joly T. (2005) Follicular morphology after ovarian cortex cryopreservation in the rabbit doe(Oryctolagus cuniculus) Gynecol Obstet Fertil 33(10): 793-8 download
Salle B, Demirci B, Franck M, Berthollet C, Lornage J. (2003) Long-term follow-up of cryopreserved hemi-ovary autografts in ewes: pregnancies, births, and histologic assessment Fertil Steril 80 (1): 172-7 download
Benchaib M, Braun V, Lornage J, Hadj S, Salle B, Lejeune H, Guerin JF (2003) Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique Human Reprod 18(5): 1023-23 download
Lornage J. (2003) Biological aspects of endometriosis in vitro fertilization J Gynecol Obstet Biol reprod (Paris) 32 (8Pt2): S48-50 download
Demirci B, Lornage J, Salle B, Poirel MT, Guerin JF, Franck M. (2003) The cryopreservation of ovarian tissue: uses and indications in veterinary medicine Theriogenology 60(6): 999-1010 download
Benchaib M, Ajina M, Lornage J, Niveleau A, Durand P, Guerin JF. (2003) Quantitation by image analysis of global DNA methylation in human spermatozoa and its prognostic value in in vitro fertilization: a preliminary study Fertil Steril 80(4): 947-53 download
Salle, B. Demirci, B. Franck, M. Rudigoz, R. C. Guerin, J. F. Lornage, J. (2002) Normal pregnancies and live births after autograft of frozen-thawed hemi-ovaries into ewes Fertil Steril 77 (2): 403-8 download
Levy R, Bourlet T, Maertens A, Salle B, Lornage J, Laurent JL, Pozzetto B, Guerin JF (2002) Pregnancy after safe IVF with hepatitis C virus RNA-positive sperm Hum Reprod 17(10): 2650-3 download
Demirci B, Salle B, Frappart L, Franck M, Guerin JF, Lornage J. (2002) Morphological alterations and DNA fragmentation in oocytes from primordial and primary follicles after freezing-thawing of ovarian cortex in sheep Fertil Steril 77(3): 595-600 download
Giscard d'Estaing S, Lornage J, Hadj S, Boulieu D, Salle B, Guerin JF. (2001) Comparison of two blastocyst culture systems: coculture on Vero cells and sequential media Fertil Steril 76(5): 1032-5 download
Demirci B, Lornage J, Salle B, Frappart L, Franck M, Guerin JF. (2001) Follicular viability and morphology of sheep ovaries after exposure to cryoprotectant and cryopreservation with different freezing protocols Fertil Steril 75(4): 754-62
Wojcik C, Benchaib M, Lornage J, Czyba JC, Guerin JF (2000) Localization of proteasomes in human oocytes and preimplantation embryos Mol Hum Reprod 6(4): 331-6 download
Wojcik C, Benchaib M, Lornage J, Czyba JC, Guerin JF. (2000) Proteasomes in human spermatozoa Int J Androl 23(3): 169-77 download
Levy R, Tardy JC, Bourlet T, Cordonier H, Mion F, Lornage J, Guerin JF. (2000) Transmission risk of hepatitis C virus in assisted reproductive techniques Hum Reprod 15(4): 810-6 download
Auger J, Eustache F, Ducot B, Blandin, T, Daudin M, Diaz I, Matribi SE, Gony B, Keskes L, Kolbezen M, Lamarte A, Lornage J, Nomal N, Pitaval G, Simon O, Virant-Klun I, Spira A, Jouannet P (2000) Intra- and inter-individual variability in human sperm concentration, motility and vitality assessment during a workshop involving ten laboratories Hum Reprod 15(11): 2360-8 download
Salle B, Lornage J, Demirci B, Vaudoyer F, Poirel MT, Franck M, Rudigoz RC, Guerin JF (1999) Restoration of ovarian steroid secretion and histologic assessment after freezing, thawing, and autograft of a hemi-ovary in sheep Fertil Steril 72 (2): 366-70 download
Levy R, Layani-Milon MP, Giscard D'Estaing S Najioullah F, Lornage J, Aymard M, Lina B (1999) Screening for Chlamydia trachomatis and Ureaplasma urealyticum infection in semen from asymptomatic male partners of infertile couples prior to in vitro fertilization Int J Androl 22(2): 113-8 download
Salle B, Lornage J, Franck M, Isoard L, Rudigoz RC, Guerin JF (1998) Freezing, thawing, and autograft of ovarian fragments in sheep: preliminary experiments and histologic assessment Fertil Steril 70 (1):124-8 download
Levy R, Najioullah F, Keppi B, Thouvenot D, Bosshard S, Lornage J, Lina B, Guerin JF, Aymard M (1997) Detection of cytomegalovirus in semen from a population of men seeking infertility evaluation Fertil Steril 68(5): 820-5 download
Levy R, Eustache F, Pilikian S, Clavel C, Cordonier H, Benchaib M, Lornage J, Pinatel MC, Guerin JF (1996) Effect of gastrin-releasing peptide on sperm functions Mol Hum Reprod 2(11): 867-72
Arbab F, Boulieu D, Bied V, Payan F, Lornage J, Guerin JF (1996) Uterine rupture in first or second trimester of pregnancy after in-vitro fertilization and embryo transfer Hum Reprod 11(5): 1120-2 download
Mathieu C, Ecochard R, Bied V, Lornage J, Czyba JC. (1995) Cumulative conception rate following intrauterine artificial insemination with husband's spermatozoa: influence of husband's age Hum reprod 10(5): 1090-7
Lornage J, Chorier H, Boulieu D, Mathieu C, Czyba JC. (1995) Six year follow-up of cryopreserved human embryos Hum reprod 10(10): 2610-6
Mathieu C, Ecochard R, Lornage J, Cordonier H, Guerin JF. (1994) Variability of the response to pentoxifylline in vitro in infertile normozoospermic and asthenozoospermic patients Arch Androl 33(1): 39-49
Mathieu C, Guerin JF, Cognat M, Lejeune H, Pinatel MC, Lornage J. (1992) Motility and fertilizing capacity of epididymal human spermatozoa in normal and pathological cases Fertil Steril 57(4): 871-6
Mathieu C, Mein M, Lornage J, Li JG, Guerin JF. (1990) Effect of spermatozoa selection on a simplified Percoll gradient in case of asthenozoospermia Andrologia 22(5): 467-71
Lornage J, Boulieu D, Mathieu C, Guerin JF, Pinatel MC, James R, Alvarado C. (1990) Transfers of frozen-thawed human embryos in cycles stimulated by HMG Hum Reprod 5(1): 60-5
Idaomar M, Guerin JF, Lornage J, Czyba JC. (1989) Stimulation of motility and energy metabolism of spermatozoa from asthenozoospermic patients by 17 beta-estradiol Arch Androl 22(3): 197-202
Guerin JF, Mathieu C, Lornage J, Pinatel MC, Boulieu D. (1989) Improvement of survival and fertilizing capacity of human spermatozoa in an IVF programme by selection on discontinuous Percoll gradients Hum Reprod 4(7): 798-804
Pilikian S, Moncharmont P, Pinatel MC, Guerin JF, Mathieu C, Lornage J. (1987) In vitro behavior of human nonfertile semen in isoosmotic and hyperosmotic media Arch Androl 18(3): 199-203
Idaomar M, Guerin JF, Lornage J, Moncharmont P, Czyba JC. (1987) Effects of estradiol and its antagonist tamoxifen on motility and metabolism of human spermatozoa Adv Contracept Deliv Syst 3(4): 337-45
Lornage J, Guerin JF, Czyba JC. (1986) Glycolytic activity of human spermatozoa in normospermic men and in men with abnormal spermograms Arch Androl 16(1): 81-8
Lornage J, Guerin JF, Czyba JC, Menezo Y (1983) Influence of cations and albumin on human spermatozoa Arch Androl 10(2): 119-25