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Conference by Adrien Meguerditchian

Published on March 28, 2017

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Delphine Delaunay


Company: Inserm U846

Mailing Address:
18, avenue Doyen Jean LÚpine

69675 - Bron Cedex - France
External Link:

Stem cells and cortical development - Teams

Research interest

The cerebral cortex is constituted by different type of neuronal cells working together to sustain most of our cognitive abilities. One critical step that ensures this higher function is the birth of the proper type and number of neurons during development.
My project will contribute to this issue by examining the mode of cell division in the mouse Neocortex during development with a special emphasis on the Wnt/planar cell polarity pathway and its function in promoting a novel division mechanism discovered during my post-doctoral studies.

Delaunay D, Robini MC, Dehay C (2015) Mitotic spindle asymmetry in rodents and primates: 2D vs. 3D measurement methodologies Front Cell Neurosci. 2015 Feb 9;9:33
Delaunay D, Cortay V, Patti D, Knoblauch K, Dehay C (2014) Mitotic spindle asymmetry: a Wnt/PCP regulated mechanism generating asymmetrical division in cortical precursors. Cell reports 6:1-15